GUT IMMUNE PROTECT

 

CLINICAL APPLICATIONS

 

  • Provides Concentrated Immunoglobulins to Enhance Mucosal Immunity
  • Helps Maintain Microbial Balance
  • Supports GI Barrier Health and Integrity
  • Helps Maintain Normal Inflammatory Balance

Gut Immune Protect is the only purified, dairy-free source of immunoglobulin G (IgG) available as a dietary supplement. Serum-derived bovine immunoglobulins (SBI) provide the highest IgG concentration available for GI and immune challenges where allergens are a significant concern. Pure IgG helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen, thereby promoting their destruction and removal from the body. Gut Immune Protect provides 1,200 mg IgG in a one- scoop serving.

Overview

Autoimmunity is on the rise globally, and recent research demonstrates a connection between autoimmunity and intestinal permeability. Furthermore, many children with attention deficit hyperactivity disorder (ADHD), autism, and other forms of neurodevelopmental delays tend to suffer from digestive issues including increased intestinal permeability (leaky gut).1, 2 If intestinal permeability continues to progress, harmful substances begin to pass into the bloodstream and the immune system becomes overactive, which causes children to experience intestinal discomfort that worsens psychiatric symptoms. 3, 4 The discovery that the gut barrier plays a key role in immune health fueled the search to strengthen it. In that search, researchers found that the binding capabilities of immunoglobulins have a positive effect on gut barrier function. 5 Immunoglobulins bind microbes and toxins in the GI tract and eliminate them prior to immune system activation. As these unwanted triggers are removed, it resets healthy immune tolerance and builds a stronger barrier to the external environment. This is a key process in reducing psychiatric symptoms that are linked to neurodevelopmental disorders (e.g., ADHD, ASD), and in doing so makes immunoglobulin supplementation beneficial for children with such disorders.

Gut Immune Protect and GI Health

The GI tract acts as the gateway to the rest of the body, making the health of the gut barrier critical to overall health. Environmental triggers like poor diet, high stress and toxin exposure can lead to GI challenges. Furthermore, individuals with behavioral, psychosocial and neurodevelopmental disorders tend to experience nutritional deficiencies, in addition to increased intestinal permeability, that worsens behavioral symptoms and overall health. 6, 7 In practice, probiotics are a natural choice for supporting beneficial bacteria in the gut, but supplementation to eliminate unwanted microbes should also be considered. Gut Immune Protect has been shown to bind microbes and toxins, further enhancing microbiome balance and facilitating gut barrier strength.8, 9 Broad- spectrum binding capabilities (See Table 1) demonstrate the positive influence of nonallergenic forms of immunoglobulins [5].1 As seen in several studies, Gut Immune Protect has the potential to bind many types of microbes and toxins.5 This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance.8, 9 In addition to improving immunity, Gut Immune Protect also helps target digestive issues such as diarrhea, while restoring the GI tract's ability to properly absorb and use essential nutrients.10 These properties not only improve immune system response, but also promote detoxification and the proper absorption of nutrients; all of which are factors that improve digestive function in children with neurodevelopmental disorders as well as their social, behavioral, and communication skills.6, 7

Gut Immune Protect and Immune Health

Occasionally, the immune system becomes overactive and immune tolerance drops. When immune tolerance is lost, the checks and balances of antibody production can be affected. To reestablish immune tolerance and appropriate activation, the burden on the immune system must be reduced. Reducing the reasons to respond allows the tissue to maintain normal inflammatory balance and creates an environment for normal tissue repair and immune reconstitution. 11, 17 Gut Immune Protect restores both immune system and GI function, which are vital for optimal physical and mental health in children with psychosocial, developmental, and behavioral disorders. In studies evaluating the effect of SBI on immune function, subjects showed positive outcomes in several areas, including inflammatory balance, gut barrier function and immune cell counts.7,8,9 In an open-label human clinical study, GI-challenged patients were given 2.5 mg SBI twice daily. They had increased CD4+ counts in the duodenum after eight weeks, indicating a regenerative effect on the tissue and immune function in the intestines. In a large, multicenter, placebo-controlled follow- up study,8 SBI led to significant increases in peripheral CD4+ cells, when compared to placebo-controlled subjects. Findings of immune reconstitution in these patient demographics is promising for the future of establishing a healthy immune system in patients with GI and immune challenges.

Directions

1 scoop (2.5 grams) in 4 ounces of water or the beverage of your choice 2 times daily or as recommended by your health care professional.

Gut Immune Protect Dosage Instructions

Start at a low dose and slowly work up to the recommended dosage over 1-2 weeks. Mix powder with approx. 4oz of beverage of choice.



Does Not Contain

Gluten, corn, yeast, artificial colors and flavors.

Cautions

If you are pregnant of nursing, consult your health care professional before taking this product.

 

 

 

 

References

  1. 1. Molloy CA, Manning-Courtney P: Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders. Autism. 2003;7(2):165-171.
  2. 2. Ming X, Chen N, et al. A Gut Feeling: A Hypothesis of the Role of the Microbiome in Attention-Deficit/Hyperactivity Disorders. Child Neurol Open. 2018;5:2329048X18786799.
  3. 3. Fasano A. Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol. 2012;10(10):1096-100.
  4. 4. Fasano A. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiol Rev. 2011; 91(1):151-75.
  5. 5. Detzel CJ, Horgan A, Henderson AL, Petschow BW, Warner CD, Maas KJ, Weaver EM. Bovine Immunoglobulin/Protein Isolate Binds Pro-Inflammatory Bacterial Compounds and Prevents Immune Activation in an Intestinal Co-Culture Model. PLOS One 10(4) April 2015; DOI:10.1371/journal.pone.0120278
  6. 6. Pae CU, Masand PS, Ajwani N, et al. Irritable bowel syndrome in psychiatric perspectives: a comprehensive review. Int J Clin Pract. 2007; 61(10):1708-18.
  7. 7. Coss-Adame E, Rao SS. Brain and gut interactions in irritable bowel syndrome: new paradigms and new understandings. Curr Gastroenterol Rep. 2014;16(4):379.
  8. 8. Jasion VS, Burnett BP. Survival and Digestibility of Orally- Administered Immunoglobulin Preparations Containing IgG Through the Gastrointestinal Tract in Humans. Nutrition Journal 2015;14:22 DOI 10.1186/s12937-015-0010-7.
  9. 9. Petschow BW, Burnett B, Shaw AL, Weaver EM, Klein GL. Serum-derived bovine immunoglobulin/protein isolate: postulated mechanism of action for management of enteropathy, Clin Exp Gastroenterology. 2014;7:181- 190.
  10. 10. Dale W. Evaluation of serum-derived bovine immunoglobulin protein isolate in subjects with diarrhea-predominant irritable bowel syndrome. Clin Med Insights Gastroenterol. 2013;6:49-50.
  11. 11. Perez-Bosque A, Miro L, Maijo M, Polo J, Campbell J, Russell L, et al. Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis. American journal of physiology Gastrointestinal and liver physiology. 2015;308(12):G1012-8.
  12. 12. Henderson AL, Brand MW, Darling RJ, Maas KJ, Detzel CJ, Hostetter J, et al. Attenuation of Colitis by Serum-Derived Bovine Immunoglobulin/Protein Isolate in a Defined Microbiota Mouse Model. Digestive diseases and sciences. 2015;60(11):3293- 303.
  13. 13. Wilson D, Evans MD, Weaver E, Shaw AL, Klein GL. Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in
  14. Subjects with Diarrhea-Predominant Irritable Bowel Syndrome. Clinical Medicine Insights: Gastroenterology. 2013;6:49-60.
  15. 14. Asmuth DM, Ma ZM, Albanese A, Sandler NG, Devaraj S, Knight TH, et al. Oral Serum- Derived Bovine Immunoglob¬ulin Improves Duodenal Immune Reconstitution and Absorption Function in Patients with HIV Enteropathy. Aids. 2013;27:2207-17.
  16. 15. Asmuth DM, Somsouk M, Hunt P, Ma ZM, Miller CL, X.D., Hinkle J, et al. Serum-Derived Bovine Immunoglobulin Protein Isolate Increases Peripheral and Mucosal CD4+ T-cell counts in Patients with HIV Enteropathy. 8th IAS Conference on HIV Pathogenesis, Treatment and
  17. 16. Prevention (AIDS 2015); MOAA02; Vancouver, Canada 19-22 July:
  18. http://www.ias2015.org/WebContent/File/IAS_2015__MED2. pdf; 2015.
  19. 17. Bosi P, Casini L, Finamore A, Cremokolini C, Merialdi G, Trevisi P, et al. Spray-dried plasma improves growth perfor¬mance and reduces inflammatory status of weaned pigs challenged with enterotoxigenic Escherichia coli K88. Journal of animal science. 2004;82(6):1764-72.
Based on 740 reviews
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Worth it!

My son is non verbal in his communication so I have been taking these vitamin capsules as well just to see if any side effects. How I give to my son to avoid any issues: Take with a full meal like lunch or dinner if with breakfast make sure it's a harty meal NOT just fruit or cereal. I use a liquid medicine syringe, open capsule and dump powder into the syringe insert plug with mouth facing up so powder isn't squirted out then I take his juice cup and draw up some apple juice into the syringe hold finger over mouth piece and shake till dissolved remove air bubble then give to him like any other liquid medicine then give him his juice cup to drink right after to avoid after tast. This way I know he got the perfect dose and don't have to worry about him drinking it in a full cup of juice and waisting it because of taste. But these are amazing for him and myself we both sleep better and have a better mood it's definitely worth it. If your child won't drink because of after taste try it this way hopefully this helps other super families love yall. And parents I'm telling you you can also take these vitamins try it. You can get liquid medicine syringe for kiddos at the local pharmacy from the pharmacist.💜

The vitamins are very good. I’ve seen so much improvement in my grandson. I referred the vitamins to at least six people, and I know that they ordered the vitamins for their child.

Calm & Focus review

Since introducing Calm & Focus into our routine, we've observed remarkable changes in our son, who has ADHD. After just two weeks, he became noticeably calmer, more balanced, and more engaged in our conversations. This supplement has been a game-changer for our toddler, and we've made it a consistent part of his daily regimen. We wholeheartedly recommend other parents to try it and witness the positive transformations firsthand.

Unpaid Review

I’ve had my kid taking this particular fish oil because it was the highest concentrated versus the others in the market. I’m really big on reading labels and focusing on product concentrations for quality. My kid has been taking this fish oil since he was about 3yrs old (level 3 ASD severe). He is now 5 (level 2 ASD moderate). He was attending ABA when we started and the therapists there had noticed changes. The other parents had asked me what I was doing and I would always refer this website. I am still purchasing this fish oil and I will continue. I will also add the D3 because kids are germy and we need strong immune systems while in kindergarten. The concentration is higher with MSH’s D3 than others from the natural herb store that I previously purchased. I am a person of numbers and results even considering the negative results for the overall benefit. The quality is worth its price and I alone- approve this message.

I'm seeing results!

I have been giving this probiotic supplement to my boy and it seems to really be helping with his speech. He has been putting words into 5/6 seven word sentences on his own, instead of using echolalia. I will continue using this for sure!

Great product

My son who is autistic has come a long way from using these products. So happy that i decided to take a step forward for his well-being. I share about these products to other parents and they have been impressed with their kid’s challenges and changes that occur each day from being nonverbal and now verbal. My son’s behavior has calm down from him having meltdowns. Thank you!

Super Magnesium Capsules

I bought the magnesium capsules for my son who has autism. He was on magnesium glycinate but it was making him very tired and weepy. These super mag capsules work much better for him. I open the capsule and mix it into his a2 milk. I started taking these too. It really helps with anxiety.

Definitely Helps

My 2 year old son has had issues with constipation and nothing helped until this probiotic powder.

Loving this stuff!

My daughter drinks this every morning in her juice and she has recently become more focused and talkative! She is also a picky eater so giving her this makes me feel better that she is still getting all the vitamins and minerals she needs. 10 stars!!!

Amazing Product

We are only on week 4 of starting the multivitamin mineral plus with our 4 1/2 year old and have seen dramatic improvement not only in his behavior but equally his speaking.
Before starting this supplement our son wasn’t even speaking in short sentences and he couldn’t or wouldn’t answer basic questions. Additionally, his behavior most days was aggressive for no reason even to our pets (our family eats pretty clean but he’s a very picky eater). We had avoided taking him out much because he would act out to others or wreck something for no reason other than being sensory overloaded.
In the last 2 weeks for consecutive days it is literally like multiple “lights” have come on and shifts have happened in his little brain.
I was not expecting to see a change this quickly. A reasonable expectation is at least 4 plus weeks. Not only have my husband and I seen it but we have had multiple friends comment that “something is different.” Last week was also the first time he stayed in his children’s class at church with me getting a call. Needless to say, we are sold and immensely grateful for this product and the Calm & Focus.

We love them!!

Since starting the MySpectrumHeros multivitamin with my 5.5 year old son he’s sleeping better, happier, hasn’t been sick as often, and seems to be even focusing better in school!!

Thank you so much for making these!!!

Definitely helped!

My two year old was struggling with hard stool and constipation for a while, but he has had soft/normal poop every day while taking this product!!! The only time he’s had a hard poop again has been the day he didn’t take the supplement. I’d recommend starting out at a super small dose and working upward to the recommended dose, because the first morning I gave it to my son, he fell asleep at 10am which never happens. The strawberry taste is pleasant. My son is an extremely picky eater and drinker, but I mix this with water and put it in his fruit smoothies and he loves it. It’s sensitive on the stomach and well-tolerated.

Optimistic

I was skeptical to try this with the reviews about the taste as my son is super picky and an always spot when I add things to his liquid or food. It mixed perfectly with a 1/4 cup warm water and then I added his flavor packet and cold water to his sippy cup. He drank it right down. Now it smells awful but I even didn't noticed a taste. We just started 2 days ago because he has slowed down on his normal eating and I also would hope it will help him with the agitation he has started at bedtime.

It really works!!!

My son has ADHD and I certainly didn’t want to put him on any medication related to his ADHD. I accidentally stumbled upon this website whilst looking for alternatives. He has been on focus and calm for almost 5 years and it’s the holy grail, to stay calm, focused and handling his emotions. It has helped to stay focused during class work.
Be patient and believe in your child and it will definitely work.

Game changer

We use in combination with the Calm & Focus and the Multimineral Vitamin. Helps with sleep, calm and his memory. Great for calcium and strengthening his immune system!

A
Calm & Focus (Copy)
Ali A.
Owsum product

I am using this product for two month and its results are miraculous

Game changer!

I feel so much better knowing my son is getting the vitamins and minerals he needs AND that it’s available in capsule form. My son refused the powder because he could taste the flavour and sense the texture. So thankful for this product.

Super Mag!

Great supplement all around! We added this to our grandson’s vitamin regimen for help with focus and concentration during school… seems to be helping!

We love the flexibility!

We love the flexibility of the capsules for my 6 year old son who takes them. He knows how to swallow pills but doesn’t always want to. With the capsule, he can choose each day how he wants to take it. He can either swallow the pill, or we’ll open it up and pour it into yogurt or a smoothie. It’s been helping with his tummy pain!

Great multivitamin

I give my son the multivitamin mineral plus twice a day and it really helps to calm him. It mixes pretty well in his juice. I add a tiny bit of room temperature water to his cold grape juice because I find the powder mixes a lot better. This vitamin actually calms him down a lot to the point where I know my son must be missing important minerals due to his autism and gi problems. I will continue to use this product because it woks. Thank you all at my spectrum hero’s for providing great products especially in powder and liquid forms 😊

Amazing results

We started this to help heal my daughter’s gut. She was having difficulty going regularly. After about a month of regularly taking this, she started going to the bathroom more frequently. It has made a tremendous difference in her overall mood. I would definitely recommend this product